Circulating Mitochondrial DAMPs Are Not Effective Inducers of Proteinuria and Kidney Injury in Rodents.

Mitochondria in eukaryotic cells are derived from bacteria in evolution. Like bacteria, mitochondria contain DNA with unmethylated CpG motifs and formyl peptides, both of which have recently been shown to be damage associated molecular patterns (DAMPs) and induce immune response and cell injury. Bas...

Full description

Bibliographic Details
Main Authors: Jing He, Yuqiu Lu, Hong Xia, Yaojun Liang, Xiao Wang, Wenduona Bao, Shifeng Yun, Yuting Ye, Chunxia Zheng, Zhihong Liu, Shaolin Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4406729?pdf=render