Immunotoxins and Anticancer Drug Conjugate Assemblies: The Role of the Linkage between Components

Immunotoxins and antibody-drug conjugates are protein-based drugs combining a target-specific binding domain with a cytotoxic domain. Such compounds are potentially therapeutic against diseases including cancer, and several clinical trials have shown encouraging results. Although the targeted elimin...

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Bibliographic Details
Main Authors: Luigi Cattel, Paola Brusa, Franco Dosio
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/3/7/848/