Cell-Penetrating Peptides—Mechanisms of Cellular Uptake and Generation of Delivery Systems

The successful clinical application of nucleic acid-based therapeutic strategies has been limited by the poor delivery efficiency achieved by existing vectors. The development of alternative delivery systems for improved biological activity is, therefore, mandatory. Since the seminal observations tw...

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Bibliographic Details
Main Authors: Sara Trabulo, Ana Luísa Cardoso, Miguel Mano, Maria C. Pedroso de Lima
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/4/961/