Impact of germline CHEK2 mutations on biochemical relapse free survival and metastasis free survival after radical treatment for patients with prostate cancer

Impact of germline CHEK2 mutations on biochemical relapse free survival and metastasis free survival after radical treatment for patients with prostate cancer

Objective: to evaluate the prognostic value of pathogenic germline BRCA1, BRCA2 and CHEK2 mutations on biochemical relapse-free survival (BRFS) and metastasis-free survival (MFS) following radical treatment in patients with localized and locally advanced prostate cancer (PCa).Materials and methods....

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Bibliographic Details
Main Authors: V. B. Matveev, A. A. Kirichek, A. V. Savinkova, A. V. Khachaturyan, D. A. Golovina, L. N. Lyubchenko
Format: Article
Language:Russian
Published: ABV-press 2019-01-01
Series:Onkourologiâ
Subjects:
prostate cancer
germline mutations
chek2
mutation i157t
mutation ivs2+1g>a
prognostic factor
biochemical relapse free survival
metastasis-free survival
Online Access:https://oncourology.abvpress.ru/oncur/article/view/889

Internet

https://oncourology.abvpress.ru/oncur/article/view/889

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