Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secre...

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Bibliographic Details
Main Authors: Lalit Kumar Dubey, Praneeth Karempudi, Sanjiv A. Luther, Burkhard Ludewig, Nicola L. Harris
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00504-9