Evolutionary potential of a duplicated repressor-operator pair: simulating pathways using mutation data.

Ample evidence has accumulated for the evolutionary importance of duplication events. However, little is known about the ensuing step-by-step divergence process and the selective conditions that allow it to progress. Here we present a computational study on the divergence of two repressors after dup...

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Bibliographic Details
Main Authors: Frank J Poelwijk, Daniel J Kiviet, Sander J Tans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1464816?pdf=render