RBBP6 interactome: RBBP6 isoform 3/DWNN and Nek6 interaction is critical for cell cycle regulation and may play a role in carcinogenesis

RBBP6 is a multidomain protein, with four splice variants translated into four functional isoforms. RBBP6 isoform 1 has been reported to interact with TP53 and pRb as well as with proteins that regulate transcriptional response to tumorigenesis such as HDM2, ZBTB38, YBX1 and NEK6. Experimental valid...

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Bibliographic Details
Main Authors: Zukile Mbita, Rodney Hull, Fortunate Mokoena, Chin-Hung Lai, Zodwa Dlamini
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914821000125