Generation of functional human hepatocytes in vitro: current status and future prospects

Abstract Liver and hepatocyte transplantation are the only effective therapies for late-stage liver diseases, in which the liver loses its regenerative capacity. However, there is a shortage of donors. As a potential alternative approach, functional hepatocytes were recently generated from various c...

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Bibliographic Details
Main Authors: Tomoko Yamaguchi, Juntaro Matsuzaki, Takeshi Katsuda, Yoshimasa Saito, Hidetsugu Saito, Takahiro Ochiya
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Inflammation and Regeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41232-019-0102-4