U-shape suppressive effect of phenol red on the epileptiform burst activity via activation of estrogen receptors in primary hippocampal culture.

Phenol red is widely used in cell culture as a pH indicator. Recently, it also has been reported to have estrogen-like bioactivity and be capable of promoting cell proliferation in different cell lines. However, the effect of phenol red on primary neuronal culture has never been investigated. By usi...

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Bibliographic Details
Main Authors: Xu Liu, Ben Chen, Lulan Chen, Wan-Ting Ren, Juan Liu, Guoxiang Wang, Wei Fan, Xin Wang, Yun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3613357?pdf=render