Pertussis Toxin Ameliorates Microglial Activation Associated With Ischemic Stroke

Pertussis Toxin Ameliorates Microglial Activation Associated With Ischemic Stroke

Objective: To investigate the effect and the underlying mechanism of Pertussis toxin (PTX) on microglia in the setting of cerebral ischemia.Methods: We tested the effect of PTX 400 ng/days on middle cerebral artery occlusion stroke model by evaluating the neurologic function, infarct size, microglia...

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Bibliographic Details
Main Authors: Feihui Zhou, Rong Liu, Pengcheng Han, Xingkui Zhang, Zhigao Li, Shen Zhang, Chang Liu, Yang Xia, Zhiwei Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
pertussis toxin
stroke
microglia
neuroprotection
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00152/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00152/full

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