Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors

Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors

Liposomes represent suitable tools for the diagnosis and treatment of a variety of diseases, including cancers. To study the role of the human epidermal growth factor receptor 2 (HER2) as target in cancer imaging and image-guided deliveries, liposomes were encapsulated with an intrinsically quenched...

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Bibliographic Details
Main Authors: Felista L. Tansi, Ronny Rüger, Claudia Böhm, Frank Steiniger, Martin Raasch, Alexander S. Mosig, Roland E. Kontermann, Ulf K. Teichgräber, Alfred Fahr, Ingrid Hilger
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
liposomes
fluorescence quenching
optical imaging
molecular targeting
HER2
tumor microenvironment
Online Access:https://www.mdpi.com/1999-4923/12/10/972

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https://www.mdpi.com/1999-4923/12/10/972

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