Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection

Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection

Pro-protein convertase subtilisin/kexin type 9 (PCSK9), a secreted serine protease, regulates serum low-density lipoprotein (LDL) cholesterol levels by targeting the degradation of LDL receptor (LDLR) in the liver. Although previous reports describe elevated levels of PCSK9 in patients with periodon...

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Bibliographic Details
Main Authors: Mai Yokoji-Takeuchi, Koichi Tabeta, Naoki Takahashi, Kei Arimatsu, Haruna Miyazawa, Yumi Matsuda-Matsukawa, Keisuke Sato, Miki Yamada, Kazuhisa Yamazaki
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Heliyon
Subjects:
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018354707

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http://www.sciencedirect.com/science/article/pii/S2405844018354707

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