Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

BACKGROUND: Cellular senescence is induced either internally, for example by replication exhaustion and cell division, or externally, for example by irradiation. In both cases, cellular damages accumulate which, if not successfully repaired, can result in senescence induction. Recently, we determine...

Full description

Bibliographic Details
Main Authors: Shiva Marthandan, Uwe Menzel, Steffen Priebe, Marco Groth, Reinhard Guthke, Matthias Platzer, Peter Hemmerich, Christoph Kaether, Stephan Diekmann
Format: Article
Language:English
Published: BMC
Series:Biological Research
Subjects:
Senescence
Fibroblasts
γ-irradiation
Aging
Transcriptome analysis
DNA repair
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100034&lng=en&tlng=en

Internet

http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100034&lng=en&tlng=en

Similar Items