In Vivo Scintigraphic Imaging of Antitumor Effects by Combined Radioiodine Therapy and Human Sodium Iodide Symporter Gene Immunotherapy
In a previous study, we demonstrated that pcDNA3.1/hNIS (human sodium iodide symporter) vaccination generated hNIS-associated CD8 + IFN-γ + (interferon-γ) T cells, which are known to be involved in antitumor immunity. However, the immune response induced was insufficient to control tumor growth in v...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2010-05-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00010 |