Evolution of exchangeable copper and relative exchangeable copper through the course of Wilson's disease in the Long Evans Cinnamon rat.

BACKGROUND: Wilson's disease (WD) is an inherited disorder of copper metabolism leading to liver failure and/or neurological impairment. Its diagnosis often remains difficult even with genetic testing. Relative exchangeable copper (REC) has recently been described as a reliable serum diagnostic...

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Bibliographic Details
Main Authors: Françoise Schmitt, Guillaume Podevin, Joël Poupon, Jérôme Roux, Pierre Legras, Jean-Marc Trocello, France Woimant, Olivier Laprévote, Tuan Huy Nguyen, Souleiman El Balkhi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866119?pdf=render