CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

Abstract Background Cisplatin (CDDP) has become a standard-of-care treatment for muscle-invasive bladder cancer (MIBC), while chemoresistance remains a major challenge. Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional entities. However, the regulatory functions a...

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Bibliographic Details
Main Authors: Hui Zhang, Xingyuan Xiao, Wenjie Wei, Chao Huang, Miao Wang, Liang Wang, Yuanqiao He, Jiayin Sun, Yangkai Jiang, Guosong Jiang, Xiaoping Zhang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Molecular Cancer
Subjects:
Bladder cancer
CDDP
CircLIFR
MSH2
Online Access:https://doi.org/10.1186/s12943-021-01360-4

Internet

https://doi.org/10.1186/s12943-021-01360-4

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