The Exon Junction Complex and intron removal prevent re-splicing of mRNA.

Accurate splice site selection is critical for fruitful gene expression. Recently, the mammalian EJC was shown to repress competing, cryptic, splice sites (SS). However, the evolutionary generality of this remains unclear. Here, we demonstrate the Drosophila EJC suppresses hundreds of functional cry...

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Bibliographic Details
Main Authors: Brian Joseph, Eric C Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009563