A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells

RUNX3 functions as a tumor suppressor in the gastric epithelium, where its inactivation is frequently observed during carcinogenesis. We identified IL23A as a RUNX3 target gene in gastric epithelial cells. This was confirmed in a series of in vitro analyses in gastric epithelial cell lines. In eluci...

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Bibliographic Details
Main Authors: Yit Teng Hor, Dominic Chih-Cheng Voon, Jason Kin Wai Koo, Huajing Wang, Wen Min Lau, Hassan Ashktorab, Shing Leng Chan, Yoshiaki Ito
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714004537