Deoxypodophyllotoxin Induces G2/M Cell Cycle Arrest and Apoptosis in SGC-7901 Cells and Inhibits Tumor Growth in Vivo

Deoxypodophyllotoxin (DPT), a natural microtubule destabilizer, was isolated from Anthriscus sylvestris, and a few studies have reported its anti-cancer effect. However, the in vivo antitumor efficacy of DPT is currently indeterminate. In this study, we investigated the anti-gastric cancer effects o...

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Bibliographic Details
Main Authors: Yu-Rong Wang, Yuan Xu, Zhen-Zhou Jiang, Mounia Guerram, Bin Wang, Xiong Zhu, Lu-Yong Zhang
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/1/1661