Clinical Significance of Galactose-Deficient IgA1 by KM55 in Patients with IgA Nephropathy

Background: Aberrant galactose-deficient IgA1 molecules (Gd-IgA1) are important causal factors in IgA nephropathy (IgAN); however, the detection of Gd-IgA1 in IgAN is complicated and instable. A monoclonal antibody, KM55, which specifically recognizes Gd-IgA1 has been developed. In the present study...

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Bibliographic Details
Main Authors: Kai Zhang, Qiongqiong Li, Yaru Zhang, Wenya Shang, Li Wei, Hongfen Li, Shan Gao, Tiekun Yan, Junya Jia, Youxia Liu, Shan Lin
Format: Article
Language:English
Published: Karger Publishers 2019-10-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:https://www.karger.com/Article/FullText/502579