Protective Effects and Mechanisms of Procyanidins on Parkinson’s Disease In Vivo and In Vitro

Protective Effects and Mechanisms of Procyanidins on Parkinson’s Disease In Vivo and In Vitro

This research assessed the molecular mechanism of procyanidins (PCs) against neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its metabolite 1-methyl-4-phenylpyridinium (MPP<sup>+</sup>) induced Parkinson’s disease (PD) models. In vitro, PC12 cells were incubated with P...

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Bibliographic Details
Main Authors: Juan Chen, Yixuan Chen, Yangfan Zheng, Jiawen Zhao, Huilin Yu, Jiajin Zhu, Duo Li
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
procyanidins
Parkinson’s disease
PC12 cells
zebrafish
Nrf2/ARE pathway
Online Access:https://www.mdpi.com/1420-3049/26/18/5558

Internet

https://www.mdpi.com/1420-3049/26/18/5558

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