Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperhomocysteinemia

Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperhomocysteinemia

Hyperhomocysteinemia (HHcy) exerts a wide range of biological effects and is associated with a number of diseases, including cardiovascular disease, dementia, neural tube defects, and cancer. Although mechanisms of HHcy toxicity are not fully uncovered, there has been a significant progress in their...

Full description

Bibliographic Details
Main Authors: Joanna Perła-Kaján, Hieronim Jakubowski
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
hyperhomocysteinemia
DNA methylation
histone
homocysteine thiolactone
<i>N</i>-homocysteinylation
miRNA
epigenetic
atherosclerosis
Alzheimer’s disease
gene expression
Online Access:https://www.mdpi.com/1422-0067/20/13/3140

Internet

https://www.mdpi.com/1422-0067/20/13/3140

Similar Items