Nucleotide sequence variation within the PI3K p85 alpha gene associates with alcohol risk drinking behaviour in adolescents.

While the phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway is typically known to regulate cell growth and survival, emerging evidence suggest a role for this pathway in regulating the behavioural responses to addictive drugs.To investigate whether PI3K contributes to patterns of risk...

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Bibliographic Details
Main Authors: Sylvane Desrivières, Kristina Krause, Anne Dyer, Josef Frank, Dorothea Blomeyer, Mark Lathrop, Karl Mann, Tobias Banaschewski, Manfred Laucht, Gunter Schumann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2262154?pdf=render