A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts

A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide; it develops in a relatively symptom-free manner, leading to rapid disease progression and metastasis, leading to a 5-year survival rate of less than 5%. A lack of dependable diagnostic markers and rapid development of...

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Bibliographic Details
Main Authors: Orla Coleman, Michael Henry, Fiona O'Neill, Sandra Roche, Niall Swan, Lorraine Boyle, Jean Murphy, Justine Meiller, Neil T. Conlon, Justin Geoghegan, Kevin C. Conlon, Vincent Lynch, Ninfa L. Straubinger, Robert M. Straubinger, Gerard McVey, Michael Moriarty, Paula Meleady, Martin Clynes
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Proteomes
Subjects:
pancreatic cancer
proteomics
ADC therapy
PDX
membrane-enriched
Online Access:https://www.mdpi.com/2227-7382/6/4/45

Internet

https://www.mdpi.com/2227-7382/6/4/45

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