Mass spectrometry-based approach for development of biomarkers in IgA nephropathy: a pilot trial

Mass spectrometry-based approach for development of biomarkers in IgA nephropathy: a pilot trial

IgA1 with galactose (Gal)-deficient hinge-region (HR) O-glycans (Gd-IgA1) plays a key role in IgA nephropathy (IgAN), and the serum level of Gd-IgA1 is elevated in the majority of IgAN patients. To characterize the involvement of IgA1 in the development and progression of IgAN, O-glycan micro-hetero...

Full description

Bibliographic Details
Main Authors: Ayako Kondo, Kazuo Takahashi, Hisateru Yamaguchi, Yuri Yoshida, Tomohiro Mizuno, Kazuki Nakajima, Hiroki Hayashi, Shigehisa Koide, Daijo Inaguma, Midori Hasegawa, Yoshiyuki Hiki, Yukio Yuzawa
Format: Article
Language:English
Published: Fujita Medical Society 2018-05-01
Series:Fujita Medical Journal
Subjects:
iga nephropathy
o-glycosylation
biomarkers
high-resolution mass spectrometry
glycopeptide isomers
Online Access:https://www.jstage.jst.go.jp/article/fmj/4/2/4_2017008/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/fmj/4/2/4_2017008/_pdf/-char/en

Similar Items