Maternal genome-wide DNA methylation patterns and congenital heart defects.

The majority of congenital heart defects (CHDs) are thought to result from the interaction between multiple genetic, epigenetic, environmental, and lifestyle factors. Epigenetic mechanisms are attractive targets in the study of complex diseases because they may be altered by environmental factors an...

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Bibliographic Details
Main Authors: Shimul Chowdhury, Stephen W Erickson, Stewart L MacLeod, Mario A Cleves, Ping Hu, Mohammad A Karim, Charlotte A Hobbs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3031146?pdf=render