IGF1/IGF1R MITOGENIC PATHWAYS AND IMPLICATIONS IN GB THERAPY

Glioblastoma (GB), the most frequent human brain cancer commonly exhibit abberant proliferation and diminished apoptosis.The neoplastic transformation of the glial cells is often related to an overexpression of growth factors and upregulation of their signaling pathways. Insulin-like growth factor 1...

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Bibliographic Details
Main Authors: Oana Alexandru, Cornelia Zaharia, Valerica Tudoric, D.O. Alexandru
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2008-03-01
Series:Romanian Journal of Neurology
Subjects:
gb
Online Access:https://revistemedicale.amaltea.ro/Romanian_Journal_of_NEUROLOGY/Revista_Romana_de_NEUROLOGIE-2008-Nr.1/RJN_2008_1_Art-01.pdf