Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.

In spite of progress in cardiovascular genetics, data on genetic background of myocardial infarction are still limited and contradictory. This applies as well to the genes involved in inflammation and coagulation processes, which play a crucial role in the disease etiopathogenesis.In this study we f...

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Main Authors: Rosa M Barsova, Dmitrijs Lvovs, Boris V Titov, Natalia A Matveeva, Roman M Shakhnovich, Tatiana S Sukhinina, Nino G Kukava, Mikhail Ya Ruda, Irina M Karamova, Timur R Nasibullin, Olga E Mustafina, German J Osmak, Ekaterina Yu Tsareva, Olga G Kulakova, Alexander V Favorov, Olga O Favorova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4675542?pdf=render