Feasibility of fluorescence energy transfer system for imaging the renoprotective effects of aliskiren in diabetic mice

Introduction: We investigated the feasibility of using a fluorescence resonance energy transfer system to image enzymatic activity in order to evaluate the effects of aliskiren (a direct renin inhibitor) on diabetic nephropathy. Materials and methods: First, we induced diabetes in C57BL/6J mice usin...

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Bibliographic Details
Main Authors: Kengo Kidokoro, Minoru Satoh, Seiji Itano, Atsunori Kuwabara, Tamaki Sasaki, Naoki Kashihara
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2016-05-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320315625704