Increased Expression of sST2 in Early HIV Infected Patients Attenuated the IL-33 Induced T Cell Responses

Increased Expression of sST2 in Early HIV Infected Patients Attenuated the IL-33 Induced T Cell Responses

T cell responses were less functional and persisted in an exhausted state in chronic HIV infection. Even in early phase of HIV infection, the dysfunction of HIV-specific T cells can be observed in rapid progressors, but the underlying mechanisms are not fully understood. Cytokines play a central rol...

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Bibliographic Details
Main Authors: Xian Wu, Yao Li, Cheng-Bo Song, Ya-Li Chen, Ya-Jing Fu, Yong-Jun Jiang, Hai-Bo Ding, Hong Shang, Zi-Ning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
IL-33
ST2
T cell response
IFN-γ
HIV infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02850/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02850/full

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