Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
How neurons produce energy to fuel fast axonal transport is only partially understood. Authors here report that most glycolytic enzymes are enriched in motile vesicles, and such glycolytic machinery can produce ATP autonomously to propel vesicle movement along microtubules in a cell-free assay.
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13233 |