Interferon-gamma impairs phagocytosis of Escherichia coli by primary murine peritoneal macrophages stimulated with LPS and differentially modulates proinflammatory cytokine release

Introduction: Interferon-γ levels are increased upon viral infections and during inflamm-aging. Resistance to infections due to Escherichia coli (E. coli), a major cause of bacteriaemia and sepsis, is impaired in aged individuals, partly due to altered phagocytic capacity and cytokine release of imm...

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Bibliographic Details
Main Authors: Sandra Schütze, Annika Kaufmann, Stephanie Bunkowski, Sandra Ribes, Roland Nau
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cytokine: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590153221000070