Learning gene networks underlying clinical phenotypes using SNP perturbation.

Availability of genome sequence, molecular, and clinical phenotype data for large patient cohorts generated by recent technological advances provides an opportunity to dissect the genetic architecture of complex diseases at system level. However, previous analyses of such data have largely focused o...

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Bibliographic Details
Main Authors: Calvin McCarter, Judie Howrylak, Seyoung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007940