A computational analysis of transcriptional profiles from CD8(+) T lymphocytes reveals potential mechanisms of HIV/AIDS control and progression

A computational analysis of transcriptional profiles from CD8(+) T lymphocytes reveals potential mechanisms of HIV/AIDS control and progression

Cytotoxic and noncytotoxic CD8+ T lymphocyte responses are essential for the control of HIV infection. Understanding the mechanisms underlying HIV control in elite controllers (ECs), which maintain undetectable viral load in the absence of antiretroviral therapy, may facilitate the development of ne...

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Bibliographic Details
Main Authors: Sergey Ivanov, Dmitry Filimonov, Olga Tarasova
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Human immunodeficiency virus
Elite controllers
CD8+ T lymphocytes
Gene expression
Cluster analysis
Master regulators
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021001689

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http://www.sciencedirect.com/science/article/pii/S2001037021001689

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