Long-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles.

The astrocyte is a major glial cell type of the brain, and plays key roles in the formation, maturation, stabilization and elimination of synapses. Thus, changes in astrocyte condition and age can influence information processing at synapses. However, whether and how aging astrocytes affect synaptic...

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Bibliographic Details
Main Authors: Hiroyuki Kawano, Shutaro Katsurabayashi, Yasuhiro Kakazu, Yuta Yamashita, Natsuko Kubo, Masafumi Kubo, Hideto Okuda, Kotaro Takasaki, Kaori Kubota, Kenichi Mishima, Michihiro Fujiwara, N Charles Harata, Katsunori Iwasaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23110166/pdf/?tool=EBI