Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

Perturbation of addition of second heart field (SHF) cardiac progenitor cells to the poles of the heart tube results in congenital heart defects (CHD). The transcriptional programs and upstream regulatory events operating in different subpopulations of the SHF remain unclear. Here, we profile the tr...

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Bibliographic Details
Main Authors: Sonia Stefanovic, Brigitte Laforest, Jean-Pierre Desvignes, Fabienne Lescroart, Laurent Argiro, Corinne Maurel-Zaffran, David Salgado, Elise Plaindoux, Christopher De Bono, Kristijan Pazur, Magali Théveniau-Ruissy, Christophe Béroud, Michel Puceat, Anthony Gavalas, Robert G Kelly, Stephane Zaffran
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
heart development
SHF
progenitor cell
cardiac differentiation
congenital heart defect
Hox
Online Access:https://elifesciences.org/articles/55124

Internet

https://elifesciences.org/articles/55124

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