A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins

<p>Abstract</p> <p>Background</p> <p>Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of predicting membrane protein topology. In a predictive task, the HMM i...

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Bibliographic Details
Main Authors: Martelli Pier, Fariselli Piero, Casadio Rita
Format: Article
Language:English
Published: BMC 2005-12-01
Series:BMC Bioinformatics