Unbiased RNA-Seq-driven identification and validation of reference genes for quantitative RT-PCR analyses of pooled cancer exosomes

Unbiased RNA-Seq-driven identification and validation of reference genes for quantitative RT-PCR analyses of pooled cancer exosomes

Abstract Background Exosomes are extracellular vesicles (EVs) derived from endocytic compartments of eukaryotic cells which contain various biomolecules like mRNAs or miRNAs. Exosomes influence the biologic behaviour and progression of malignancies and are promising candidates as non-invasive diagno...

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Bibliographic Details
Main Authors: Yao Dai, Yumeng Cao, Jens Köhler, Aiping Lu, Shaohua Xu, Haiyun Wang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Genomics
Subjects:
Reference gene
qRT-PCR
Cancer exosome
RNA-Seq
miRNA-Seq
Online Access:https://doi.org/10.1186/s12864-020-07318-y

Internet

https://doi.org/10.1186/s12864-020-07318-y

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