Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage
<p>Abstract</p> <p>Background</p> <p>CDC25B phosphatase is a cell cycle regulator that plays a critical role in checkpoint control. Up-regulation of CDC25B expression has been documented in a variety of human cancers, however, the relationships with the alteration of th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/29 |