Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage

<p>Abstract</p> <p>Background</p> <p>CDC25B phosphatase is a cell cycle regulator that plays a critical role in checkpoint control. Up-regulation of CDC25B expression has been documented in a variety of human cancers, however, the relationships with the alteration of th...

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Bibliographic Details
Main Authors: Schmitt Estelle, Bugler Béatrix, Aressy Bernadette, Ducommun Bernard
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/29