Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads

Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads

Viral infections and reactivations remain a serious obstacle to successful hematopoietic stem cell transplantation (HSCT). When antiviral drug treatment fails, adoptive virus-specific T-cell transfer provides an effective alternative. Assuming that naive T cells (T<sub>N</sub>) are mainl...

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Bibliographic Details
Main Authors: Caroline Mangare, Sabine Tischer-Zimmermann, Sebastian B. Riese, Anna C. Dragon, Immo Prinz, Rainer Blasczyk, Britta Maecker-Kolhoff, Britta Eiz-Vesper
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
cytomegalovirus (CMV)
donor lymphocyte infusions (DLIs)
graft versus host disease (GvHD)
naive T-cell depletion
Online Access:https://www.mdpi.com/1422-0067/20/6/1415

Internet

https://www.mdpi.com/1422-0067/20/6/1415

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