Calcium chelation by alginate activates the type III secretion system in mucoid Pseudomonas aeruginosa biofilms.

The extracellular biofilm matrix includes primarily DNA and exopolysaccharides (EPS), which function to maintain aggregate structures and to protect biofilms from antibiotics and the immune response. Both polymers are anionic and have cation binding activity, however the impact of this activity on b...

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Bibliographic Details
Main Authors: Shawn R Horsman, Richard A Moore, Shawn Lewenza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466208?pdf=render