PRIMITIVE ATP-ACTIVATED P2X RECEPTORS: DISCOVERY, FUNCTION AND PHARMACOLOGY

Adenosine 5-triphosphate (ATP) is omnipresent in biology. It is therefore no surprise that organisms have evolved multifaceted roles for ATP, exploiting its abundance and restriction of passive diffusion across biological membranes. A striking role is the emergence of ATP as a bona fide transmitte...

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Bibliographic Details
Main Author: Samuel J Fountain
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00247/full