Sensory Neurons Derived from Diabetic Rats Have Diminished Internal Ca Stores Linked to Impaired Re-uptake by the Endoplasmic Reticulum

Distal symmetrical sensory neuropathy in diabetes involves the dying back of axons, and the pathology equates with axonal dystrophy generated under conditions of aberrant Ca 2+ signalling. Previous work has described abnormalities in Ca 2+ homoeostasis in sensory and dorsal horn neurons acutely isol...

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Bibliographic Details
Main Authors: Elena Zherebitskaya, Jason Schapansky, Eli Akude, Darrell R Smith, Randy Van der Ploeg, Natasha Solovyova, Alexei Verkhratsky, Paul Fernyhough
Format: Article
Language:English
Published: SAGE Publishing 2011-12-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20110038