Discovery of rare ancestry-specific variants in the fetal genome that confer risk of preterm premature rupture of membranes (PPROM) and preterm birth

Discovery of rare ancestry-specific variants in the fetal genome that confer risk of preterm premature rupture of membranes (PPROM) and preterm birth

Abstract Background Preterm premature rupture of membranes (PPROM) is the leading identifiable cause of preterm birth, a complication that is more common in African Americans. Attempts to identify genetic loci associated with preterm birth using genome-wide association studies (GWAS) have only been...

Full description

Bibliographic Details
Main Authors: Bhavi P. Modi, Hardik I. Parikh, Maria E. Teves, Rewa Kulkarni, Jiang Liyu, Roberto Romero, Timothy P. York, Jerome F. Strauss
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medical Genetics
Subjects:
Preterm premature rupture of membranes
Defensin β1
Mannose binding lectin-2
Methyltransferase like 7B
Whole exome sequencing
Online Access:http://link.springer.com/article/10.1186/s12881-018-0696-4

Internet

http://link.springer.com/article/10.1186/s12881-018-0696-4

Similar Items