Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2

<p>Abstract</p> <p>Background</p> <p>Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T-cell leukemia (ATL), whereas its relative HTLV-2 is not associated with any malignancies including ATL. HTLV-1 Tax1 transformed a T-cell line from interleuki...

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Bibliographic Details
Main Authors: Tanaka Yuetsu, Oie Masayasu, Takahashi Masahiko, Kondo Rie, Higuchi Masaya, Shoji Toshiyuki, Aoyagi Yutaka, Fujii Masahiro
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/83