Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket.

Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket.

Virtually all DNA viruses including hepatitis B viruses (HBV) replicate their genome inside the nucleus. In non-dividing cells, the genome has to pass through the nuclear pore complexes (NPCs) by the aid of nuclear transport receptors as e.g. importin beta (karyopherin). Most viruses release their g...

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Bibliographic Details
Main Authors: André Schmitz, Alexandra Schwarz, Michael Foss, Lixin Zhou, Birgit Rabe, Julia Hoellenriegel, Miriam Stoeber, Nelly Panté, Michael Kann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2813275?pdf=render

Internet

http://europepmc.org/articles/PMC2813275?pdf=render

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