Nitrogen isotopes provide clues to amino acid metabolism in human colorectal cancer cells

Abstract Glutamic acid and alanine make up more than 60 per cent of the total amino acids in the human body. Glutamine is a significant source of energy for cells and also a prime donor of nitrogen in the biosynthesis of many amino acids. Several studies have advocated the role of glutamic acid in c...

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Bibliographic Details
Main Authors: R. V. Krishnamurthy, Yogesh R. Suryawanshi, Karim Essani
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02793-y