BMP-2 and titanium particles synergistically activate osteoclast formation

BMP-2 and titanium particles synergistically activate osteoclast formation

A previous study showed that BMP-2 (bone morphogenetic protein-2) and wear debris can separately support osteoclast formation induced by the receptor activator of NF-κB ligand (RANKL). However, the effect of BMP-2 on wear debris-induced osteoclast formation is unclear. In this study, we show that ne...

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Bibliographic Details
Main Authors: S.X. Sun, H.H. Guo, J. Zhang, B. Yu, K.N. Sun, Q.H. Jin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Bone morphogenetic protein
Titanium
Osteoclasts
SMAD
RANKL
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000600461&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000600461&lng=en&tlng=en

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