Putative endothelial progenitor cells do not promote vascular repair but attenuate pericyte–myofibroblast transition in UUO-induced renal fibrosis

Putative endothelial progenitor cells do not promote vascular repair but attenuate pericyte–myofibroblast transition in UUO-induced renal fibrosis

Abstract Background Putative endothelial progenitor cells (pEPCs) have been confirmed to participate in alleviation of renal fibrosis in several ischaemic diseases. However, their mechanistic effect on renal fibrosis, which is characterized by vascular regression and further rarefaction-related path...

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Bibliographic Details
Main Authors: Juan Yang, Meng Wang, Fengming Zhu, Jie Sun, Huzi Xu, Octavia Li-Sien Chong Lee Shin, Zhi Zhao, Guangchang Pei, Han Zhu, Chujin Cao, Xiaofeng He, Yi Huang, Zufu Ma, Liu Liu, Le Wang, Yong Ning, Wei Liu, Gang Xu, Xiaohui Wang, Rui Zeng, Ying Yao
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Putative endothelial progenitor cells
Microvesicles
Renal fibrosis
Pericyte–myofibroblast transition
Online Access:http://link.springer.com/article/10.1186/s13287-019-1201-5

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http://link.springer.com/article/10.1186/s13287-019-1201-5

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