PEP06 polypeptide 30 is a novel cluster-dissociating agent inhibiting αv integrin/FAK/Src signaling in oral squamous cell carcinoma cells

Collectively migrating tumor cells have been recently implicated in enhanced metastasis of epithelial malignancies. In oral squamous cell carcinoma (OSCC), αv integrin is a crucial mediator of multicellular clustering and collective movement in vitro; however, its contribution to metastatic spread r...

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Bibliographic Details
Main Authors: Gulnara Tuguzbaeva, Er Yue, Xi Chen, Lina He, Xinlei Li, Jiaming Ju, Ying Qin, Valentin Pavlov, Yanjie Lu, Wenting Jia, Yunlong Bai, Yumei Niu, Baofeng Yang
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519309293